Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits NF-kappaB-inducing kinase activity. Involved in I-kappaB kinase/NF-kappaB signaling and immune response. Predicted to localize to cytosol; fibrillar center; and nucleoplasm. Is expressed in several structures, including alimentary system; cardiovascular system; nervous system; sensory organ; and skeleton. Used to study Sjogren's syndrome and primary biliary cholangitis. Orthologous to human MAP3K14 (mitogen-activated protein kinase kinase kinase 14).