Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits DNA-directed DNA polymerase activity and identical protein binding activity. Involved in in utero embryonic development; mitochondrion organization; and respiratory electron transport chain. Localizes to mitochondrion. Is expressed in early conceptus and secondary oocyte. Human ortholog(s) of this gene implicated in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 4 and mitochondrial DNA depletion syndrome. Orthologous to human POLG2 (DNA polymerase gamma 2, accessory subunit).