Automated description from the Alliance of Genome Resources (Release 5.3.0)
Enables DNA-directed DNA polymerase activity and identical protein binding activity. Acts upstream of or within in utero embryonic development; mitochondrion organization; and respiratory electron transport chain. Located in mitochondrion. Is expressed in early conceptus and secondary oocyte. Used to study nephrocalcinosis. Human ortholog(s) of this gene implicated in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 4 and mitochondrial DNA depletion syndrome. Orthologous to human POLG2 (DNA polymerase gamma 2, accessory subunit).