Automated description from the Alliance of Genome Resources (Release 5.2.2)
Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Involved in G1/S transition of mitotic cell cycle; negative regulation of protein localization to nucleus; and regulation of transforming growth factor beta receptor signaling pathway. Acts upstream of or within several processes, including hippo signaling; inner cell mass cell differentiation; and keratinocyte differentiation. Located in spindle pole. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and immune system. Orthologous to human LATS2 (large tumor suppressor kinase 2).