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Gene Ontology Classifications
Symbol
Name
ID
Nr2f2
nuclear receptor subfamily 2, group F, member 2
MGI:1352452

Go Annotations as Summary Text (Tabular View) (GO Graph)

GO curators for mouse genes have assigned the following annotations to the gene product of Nr2f2. (This text reflects annotations as of Thursday, July 24, 2014.)
Summary from NCBI RefSeq


[Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the steroid thyroid hormone superfamily of nuclear receptors. The encoded protein is a ligand inducible transcription factor that is involved in the regulation of many different genes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
Summary text based on GO annotations supported by experimental evidence in mouse
Summary text based on GO annotations supported by experimental evidence in other organisms
Summary text based on GO annotations supported by structural data
Summary text for additional MGI annotations
References
  1. Ben-Shushan E et al. (1995) A dynamic balance between ARP-1/COUP-TFII, EAR-3/COUP-TFI, and retinoic acid receptor:retinoid X receptor heterodimers regulates Oct-3/4 expression in embryonal carcinoma cells. Mol Cell Biol, 15:1034-48. (PubMed:7823919)
  2. Berenson LS et al. (2004) Issues in T-helper 1 development--resolved and unresolved. Immunol Rev, 202:157-74. (PubMed:15546392)
  3. Kyrmizi I et al. (2006) Plasticity and expanding complexity of the hepatic transcription factor network during liver development. Genes Dev, 20:2293-305. (PubMed:16912278)
  4. Nishiyama A et al. (2009) Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors. Cell Stem Cell, 5:420-33. (PubMed:19796622)
  5. Petit FG et al. (2007) Deletion of the orphan nuclear receptor COUP-TFII in uterus leads to placental deficiency. Proc Natl Acad Sci U S A, 104:6293-8. (PubMed:17404209)
  6. Takamoto N et al. (2005) COUP-TFII is essential for radial and anteroposterior patterning of the stomach. Development, 132:2179-89. (PubMed:15829524)
  7. Tripodi M et al. (2004) The COUP-TF nuclear receptors regulate cell migration in the mammalian basal forebrain. Development, 131:6119-29. (PubMed:15548577)
  8. You LR et al. (2005) Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity. Nature, 435:98-104. (PubMed:15875024)
  9. You LR et al. (2005) Mouse lacking COUP-TFII as an animal model of Bochdalek-type congenital diaphragmatic hernia. Proc Natl Acad Sci U S A, 102:16351-6. (PubMed:16251273)



Go Annotations in Tabular Form (Text View) (GO Graph)

 
 


Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  ISS Inferred from sequence or structural similarity
  ISO Inferred from sequence orthology
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  NAS Non-traceable author statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory