Automated description from the Alliance of Genome Resources (Release 3.0)
Contributes to ubiquitin protein ligase activity. Involved in several processes, including cellular protein metabolic process; mitotic cell cycle phase transition; and positive regulation of intracellular estrogen receptor signaling pathway. Localizes to SCF ubiquitin ligase complex. Human ortholog(s) of this gene implicated in prostate carcinoma. Is expressed in several structures, including blastocyst; compacted morula; and retina nuclear layer. Orthologous to human SKP2 (S-phase kinase associated protein 2).