Automated description from the Alliance of Genome Resources
Predicted to have several functions, including integrin binding activity; ion channel binding activity; and protein homodimerization activity. Involved in positive regulation of ATPase activity; positive regulation of gene expression; and regulation of calcium ion transport. Predicted to localize to several cellular components, including the apical plasma membrane; basolateral plasma membrane; and neuronal cell body. Used to study autosomal dominant hypocalcemia 1; familial hypocalciuric hypercalcemia 1; and hyperparathyroidism. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant hypocalcemia (multiple); hypercalcemia (multiple); hyperparathyroidism (multiple); idiopathic generalized epilepsy; and nephrolithiasis. Orthologous to human CASR (calcium sensing receptor).