Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables ATP binding activity and protein serine/threonine kinase activity. Involved in positive regulation of cell-substrate junction organization; positive regulation of intracellular signal transduction; and positive regulation of keratinocyte migration. Located in focal adhesion. Is expressed in several structures, including genitourinary system; molar; nervous system; neural retina; and skin. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and lung adenocarcinoma. Orthologous to human MAP4K4 (mitogen-activated protein kinase kinase kinase kinase 4).