Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits nucleosomal DNA binding activity and promoter-specific chromatin binding activity. Involved in negative regulation of transcription of nucleolar large rRNA by RNA polymerase I; regulation of lipid metabolic process; and regulation of response to oxidative stress. Localizes to condensed chromosome and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human MACROH2A1 (macroH2A.1 histone).