Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits alpha-tubulin binding activity and microtubule binding activity. Involved in several processes, including muscle cell development; myeloid cell activation involved in immune response; and negative regulation of macromolecule metabolic process. Localizes to several cellular components, including T-tubule; lamellipodium; and membrane microdomain. Is expressed in heart ventricle. Used to study autosomal recessive limb-girdle muscular dystrophy type 2B and distal myopathy. Human ortholog(s) of this gene implicated in Miyoshi muscular dystrophy 1; autosomal recessive limb-girdle muscular dystrophy type 2B; distal muscular dystrophy with anterior tibial onset; and muscular dystrophy. Orthologous to human DYSF (dysferlin).