Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits extracellular matrix binding activity and heparin binding activity. Involved in defense response to bacterium and negative regulation of cold-induced thermogenesis. Localizes to extracellular space. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and immune system. Human ortholog(s) of this gene implicated in osteoarthritis. Orthologous to human ADAMTS5 (ADAM metallopeptidase with thrombospondin type 1 motif 5).