Automated description from the Alliance of Genome Resources
Predicted to have protein kinase binding activity and protein serine/threonine kinase activator activity. Involved in several processes, including cellular response to leukemia inhibitory factor; lung development; and negative regulation of signal transduction. Localizes to several cellular components, including the cytoskeleton; cytosol; and nucleus. Used to study achalasia and neuronal intestinal dysplasia. Human ortholog(s) of this gene implicated in IgA glomerulonephritis. Orthologous to human SPRY2 (sprouty RTK signaling antagonist 2).