Automated description from the Alliance of Genome Resources (Release 4.0)
Enables protein kinase binding activity. Involved in autophagosome assembly. Acts upstream of or within several processes, including positive regulation of cell size; regulation of signal transduction; and reticulophagy. Located in autophagosome membrane; nucleus; and phagophore assembly site membrane. Part of Atg1/ULK1 kinase complex. Is expressed in several structures, including heart; musculoskeletal system; nervous system; and trunk paraxial mesenchyme. Human ortholog(s) of this gene implicated in breast cancer. Orthologous to human RB1CC1 (RB1 inducible coiled-coil 1).