Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables chromatin DNA binding activity and protein O-acetylglucosaminyltransferase activity. Involved in several processes, including mitophagy; positive regulation of cold-induced thermogenesis; and regulation of gene expression. Acts upstream of or within protein O-linked glycosylation. Is active in glutamatergic synapse and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 106. Orthologous to human OGT (O-linked N-acetylglucosamine (GlcNAc) transferase).