Automated description from the Alliance of Genome Resources
Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and transcription corepressor activity. Involved in negative regulation of transcription by RNA polymerase II. Localizes to the ESC/E(Z) complex. Used to study Hirschsprung's disease and Waardenburg's syndrome. Is expressed in autopod; brain; early conceptus; genitourinary system; and thymus primordium. Orthologous to human AEBP2 (AE binding protein 2).