Automated description from the Alliance of Genome Resources
Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II core promoter sequence-specific DNA binding activity; and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in mitochondrion organization. Predicted to localize to the cytosol and nucleoplasm. Human ortholog(s) of this gene implicated in Huntington's disease. Is expressed in several structures, including branchial arch; connective tissue; genitourinary system; otic capsule; and skeleton. Orthologous to human NRF1 (nuclear respiratory factor 1).