Automated description from the Alliance of Genome Resources (Release 3.2)
Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II core promoter sequence-specific DNA binding activity. Involved in mitochondrion organization. Predicted to localize to cytosol and nucleoplasm. Is expressed in several structures, including branchial arch; connective tissue; genitourinary system; otic capsule; and skeleton. Human ortholog(s) of this gene implicated in Huntington's disease. Orthologous to human NRF1 (nuclear respiratory factor 1).