Automated description from the Alliance of Genome Resources (Release 3.1.1)
Involved in ERAD pathway; protein secretion; and triglyceride metabolic process. Predicted to localize to Derlin-1 retrotranslocation complex and Hrd1p ubiquitin ligase ERAD-L complex. Is expressed in several structures, including genitourinary system; liver; neural tube; pancreas parenchyma; and spleen. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human SEL1L (SEL1L adaptor subunit of ERAD E3 ubiquitin ligase).