Automated description from the Alliance of Genome Resources
Exhibits RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in several processes, including animal organ development; regulation of transcription by RNA polymerase II; and transmembrane receptor protein serine/threonine kinase signaling pathway. Localizes to the cytoplasm and nucleus. Orthologous to human SMAD5 (SMAD family member 5).