Automated description from the Alliance of Genome Resources (Release 4.0)
Is predicted to enable cytokine activity. Involved in several processes, including blood vessel morphogenesis; positive regulation of BMP signaling pathway; and positive regulation of endothelial cell differentiation. Acts upstream of or within osteoblast differentiation; positive regulation of gene expression; and positive regulation of transcription by RNA polymerase II. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including central nervous system; ileum; interphalangeal joint; liver; and male reproductive gland or organ. Human ortholog(s) of this gene implicated in hereditary hemorrhagic telangiectasia. Orthologous to human GDF2 (growth differentiation factor 2).