Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables 1-phosphatidylinositol-4-phosphate 5-kinase activity. Involved in regulation of postsynaptic neurotransmitter receptor internalization and regulation of synaptic vesicle endocytosis. Acts upstream of or within axonogenesis; phosphatidylinositol biosynthetic process; and platelet aggregation. Located in cytosol. Is active in glutamatergic synapse and postsynaptic density. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; peripheral nervous system ganglion; and sensory organ. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome 3. Orthologous to human PIP5K1C (phosphatidylinositol-4-phosphate 5-kinase type 1 gamma).