Automated description from the Alliance of Genome Resources (Release 5.2.0)
Predicted to enable several functions, including PDZ domain binding activity; cation channel activity; and identical protein binding activity. Involved in cellular response to cAMP and regulation of membrane depolarization. Acts upstream of or within regulation of membrane potential. Part of HCN channel complex. Is expressed in heart; heart ventricle; spinal cord; and ventral grey horn. Human ortholog(s) of this gene implicated in familial febrile seizures 2. Orthologous to human HCN2 (hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2).