Automated description from the Alliance of Genome Resources
Exhibits Wnt-activated receptor activity and Wnt-protein binding activity. Involved in several processes, including animal organ development; cell surface receptor signaling pathway involved in cell-cell signaling; and embryonic morphogenesis. Localizes to the mitochondrion. Used to study exudative vitreoretinopathy and osteoporosis-pseudoglioma syndrome. Human ortholog(s) of this gene implicated in bone remodeling disease (multiple); eye disease (multiple); osteoporosis-pseudoglioma syndrome; and polycystic liver disease. Orthologous to human LRP5 (LDL receptor related protein 5).