Automated description from the Alliance of Genome Resources
Exhibits arachidonate 12-lipoxygenase activity and linoleate 9S-lipoxygenase activity. Involved in several processes, including ceramide biosynthetic process; establishment of skin barrier; and long-chain fatty acid metabolic process. Predicted to localize to the cytoplasm. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 2. Orthologous to human ALOX12B (arachidonate 12-lipoxygenase, 12R type).