Automated description from the Alliance of Genome Resources (Release 4.1.0)
Enables nucleic acid binding activity and promoter-specific chromatin binding activity. Acts upstream of or within several processes, including histone modification; negative regulation of transcription by RNA polymerase II; and oligodendrocyte differentiation. Located in nucleus and sex chromatin. Part of nucleus; protein-DNA complex; and ribonucleoprotein complex. Is expressed in several structures, including bone; central nervous system; genitourinary system; limb; and neural retina. Orthologous to human SUZ12 (SUZ12 polycomb repressive complex 2 subunit).