Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables proton-transporting ATPase activity, rotational mechanism. Involved in synaptic vesicle lumen acidification. Located in apical plasma membrane; cytosol; and microvillus. Part of proton-transporting V-type ATPase, V1 domain and transmembrane transporter complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Human ortholog(s) of this gene implicated in autosomal recessive cutis laxa type IID and developmental and epileptic encephalopathy 93. Orthologous to human ATP6V1A (ATPase H+ transporting V1 subunit A).