Automated description from the Alliance of Genome Resources
Exhibits several functions, including DNA-binding transcription factor activity; RNA polymerase II regulatory region sequence-specific DNA binding activity; and nuclear hormone receptor binding activity. Involved in positive regulation of transcription by RNA polymerase II and retina development in camera-type eye. Localizes to the nucleus and transcription factor complex. Used to study Leber congenital amaurosis 7. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 7 and cone-rod dystrophy 2. Is expressed in several structures, including eye; face; and nervous system. Orthologous to human CRX (cone-rod homeobox).