Automated description from the Alliance of Genome Resources
Exhibits extracellularly ATP-gated cation channel activity. Involved in several processes, including neuromuscular synaptic transmission; response to ATP; and smooth muscle contraction. Localizes to the Schaffer collateral - CA1 synapse; axon; and hippocampal mossy fiber to CA3 synapse. Is expressed in several structures, including branchial arch; embryo ectoderm; nervous system; retina; and skin. Orthologous to human P2RX3 (purinergic receptor P2X 3).