Automated description from the Alliance of Genome Resources
Exhibits several functions, including SMAD binding activity; beta-catenin binding activity; and enzyme binding activity. Involved in several processes, including chordate embryonic development; positive regulation of cellular protein metabolic process; and regulation of transcription, DNA-templated. Localizes to several cellular components, including the Wnt signalosome; beta-catenin destruction complex; and cell cortex. Colocalizes with the cytoplasmic microtubule. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Is expressed in several structures, including forebrain; jaw; lung; retina; and urinary system. Orthologous to human AXIN1 (axin 1).