Automated description from the Alliance of Genome Resources (Release 3.1.1)
Predicted to have several functions, including D2 dopamine receptor binding activity; enzyme binding activity; and protein domain specific binding activity. Involved in circulatory system development and synaptic vesicle endocytosis. Localizes to clathrin-coated pit and photoreceptor inner segment. Predicted to colocalize with growth cone. Is expressed in central nervous system; retina; and skin. Used to study centronuclear myopathy and cystic kidney disease. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease dominant intermediate B; centronuclear myopathy 1; and lethal congenital contracture syndrome. Orthologous to human DNM2 (dynamin 2).