Automated description from the Alliance of Genome Resources
Exhibits DNA-binding transcription factor activity; nucleic acid binding activity; and protein homodimerization activity. Involved in several processes, including SMAD protein signal transduction; animal organ development; and regulation of transcription by RNA polymerase II. Localizes to the cytoplasm; nucleus; and transcription factor complex. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; nervous system; and sensory organ. Orthologous to human SMAD1 (SMAD family member 1).