Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable several functions, including C4-dicarboxylate transmembrane transporter activity; inorganic anion transmembrane transporter activity; and oxidative phosphorylation uncoupler activity. Involved in several processes, including cellular response to glucose stimulus; macrophage differentiation; and positive regulation of cold-induced thermogenesis. Acts upstream of or within negative regulation of neuron apoptotic process. Located in mitochondrial membrane. Is expressed in several structures, including alimentary system; cerebral cortex; hemolymphoid system; integumental system; and nose. Used to study polycystic liver disease. Human ortholog(s) of this gene implicated in artery disease (multiple); diabetic neuropathy; end stage renal disease; metabolic dysfunction-associated steatotic liver disease; and obesity. Orthologous to human UCP2 (uncoupling protein 2).