Automated description from the Alliance of Genome Resources
Predicted to have oxidative phosphorylation uncoupler activity. Involved in positive regulation of cold-induced thermogenesis and regulation of mitochondrial membrane potential. Localizes to the mitochondrion. Used to study polycystic liver disease. Human ortholog(s) of this gene implicated in artery disease (multiple); diabetic neuropathy; end stage renal failure; non-alcoholic fatty liver disease; and obesity. Is expressed in several structures, including adipose tissue; hemolymphoid system; integumental system; nose; and skeletal muscle. Orthologous to human UCP2 (uncoupling protein 2).