Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables SH2 domain binding activity. Involved in several processes, including cell surface receptor signaling pathway; cellular response to lipopolysaccharide; and endodermal cell fate commitment. Acts upstream of or within blastocyst development and negative regulation of gene expression, epigenetic. Located in nucleus. Part of Cdc73/Paf1 complex and euchromatin. Is expressed in cerebral cortex and telencephalon. Orthologous to human CTR9 (CTR9 homolog, Paf1/RNA polymerase II complex component).