Automated description from the Alliance of Genome Resources (Release 3.1.1)
Predicted to have fibroblast growth factor binding activity and identical protein binding activity. Involved in generation of neurons; microtubule depolymerization; and positive regulation of RNA splicing. Localizes to several cellular components, including COPI-coated vesicle; Cajal body; and growth cone. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and hemolymphoid system gland. Used to study Werdnig-Hoffmann disease and juvenile spinal muscular atrophy. Human ortholog(s) of this gene implicated in Werdnig-Hoffmann disease; adult spinal muscular atrophy; intermediate spinal muscular atrophy; juvenile spinal muscular atrophy; and spinal muscular atrophy. Orthologous to several human genes including SMN2 (survival of motor neuron 2, centromeric).