Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within negative regulation of neuron differentiation and neuron differentiation. Located in nucleus. Is expressed in several structures, including central nervous system; embryo ectoderm; genitourinary system; retina; and spinal component of peripheral nervous system. Orthologous to human ISL2 (ISL LIM homeobox 2).