Automated description from the Alliance of Genome Resources
Exhibits ubiquitin protein ligase activity. Involved in several processes, including chordate embryonic development; myeloid leukocyte differentiation; and positive regulation of cytokine biosynthetic process. Localizes to several cellular components, including the CD40 receptor complex; cytoplasmic side of plasma membrane; and lipid droplet. Used to study hypohidrotic ectodermal dysplasia. Is expressed in several structures, including future brain; lower jaw; mandibular process; reproductive system; and sensory organ. Orthologous to human TRAF6 (TNF receptor associated factor 6).