Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables protein serine/threonine kinase activity. Involved in several processes, including positive regulation of amyloid-beta formation; regulation of cellular biosynthetic process; and regulation of signal transduction. Acts upstream of or within extrinsic apoptotic signaling pathway via death domain receptors; nervous system development; and positive regulation of centrosome duplication. Located in spindle pole centrosome. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Is expressed in several structures, including central nervous system; genitourinary system; heart; musculature; and somite. Orthologous to human ROCK2 (Rho associated coiled-coil containing protein kinase 2).