Automated description from the Alliance of Genome Resources (Release 3.0)
Exhibits lipoprotein particle binding activity; lipoteichoic acid immune receptor activity; and low-density lipoprotein particle receptor activity. Involved in several processes, including lipid transport; positive regulation of cytokine production; and response to bacterium. Localizes to several cellular components, including brush border membrane; external side of plasma membrane; and membrane raft. Used to study platelet-type bleeding disorder 10. Human ortholog(s) of this gene implicated in several diseases, including hemolytic-uremic syndrome; osteoarthritis; pemphigus; platelet-type bleeding disorder 10; and type 2 diabetes mellitus. Is expressed in several structures, including Meckel's cartilage; axial skeleton; bone; hindlimb; and telencephalon. Orthologous to human CD36 (CD36 molecule).