Automated description from the Alliance of Genome Resources
Exhibits amyloid-beta binding activity; transcription factor binding activity; and ubiquitin protein ligase binding activity. Involved in several processes, including generation of neurons; negative regulation of thymidylate synthase biosynthetic process; and positive regulation of nucleobase-containing compound metabolic process. Localizes to several cellular components, including the Schaffer collateral - CA1 synapse; glutamatergic synapse; and neuromuscular junction. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human APBB1 (amyloid beta precursor protein binding family B member 1).