Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables DNA-binding transcription factor binding activity. Involved in dorsal/ventral axis specification; negative regulation of transcription by RNA polymerase II; and regulation of signal transduction. Acts upstream of or within embryonic skeletal system morphogenesis and trophoblast giant cell differentiation. Located in nucleus. Is expressed in several structures, including medulla oblongata basal plate mantle layer; placenta; sensory organ; skeleton; and trophectoderm. Orthologous to human MDFI (MyoD family inhibitor).