Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits anion:anion antiporter activity; bicarbonate transmembrane transporter activity; and chloride transmembrane transporter activity. Involved in several processes, including cellular response to cAMP; membrane hyperpolarization; and sperm capacitation. Localizes to membrane and sperm midpiece. Used to study congenital secretory chloride diarrhea 1. Human ortholog(s) of this gene implicated in congenital secretory chloride diarrhea 1 and diarrhea. Orthologous to human SLC26A3 (solute carrier family 26 member 3).