Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits chromatin binding activity. Involved in several processes, including DNA metabolic process; cellular response to leukemia inhibitory factor; and chromatin organization involved in negative regulation of transcription. Localizes to nucleus and pericentric heterochromatin. Is expressed in several structures, including central nervous system; gut; neural retina; reproductive system; and thymus. Human ortholog(s) of this gene implicated in immunodeficiency-centromeric instability-facial anomalies syndrome 4. Orthologous to human HELLS (helicase, lymphoid specific).