Automated description from the Alliance of Genome Resources
Exhibits C-C chemokine binding activity and C-C chemokine receptor activity. Involved in several processes, including leukocyte migration; positive regulation of cell migration; and positive regulation of cytokine production. Localizes to the external side of plasma membrane. Used to study age related macular degeneration. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; aggressive periodontitis; coronary artery disease (multiple); diabetes mellitus (multiple); and uveitis (multiple). Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human CCR2 (C-C motif chemokine receptor 2).