Automated description from the Alliance of Genome Resources
Predicted to have serine-type endopeptidase activity. Involved in complement activation, alternative pathway. Predicted to localize to the extracellular space. Human ortholog(s) of this gene implicated in several diseases, including atypical hemolytic-uremic syndrome; eye disease (multiple); glomerulonephritis (multiple); precursor lymphoblastic lymphoma/leukemia; and sickle cell anemia. Orthologous to human CFB (complement factor B).