Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits DNA replication origin binding activity; enzyme binding activity; and histone binding activity. Predicted to contribute to 3'-5' DNA helicase activity. Involved in DNA unwinding involved in DNA replication; cellular response to interleukin-4; and nucleosome assembly. Localizes to nuclear origin of replication recognition complex. Is expressed in several structures, including central nervous system; future brain; inner cell mass; limb; and vertebral axis musculature. Human ortholog(s) of this gene implicated in Alzheimer's disease and autosomal dominant nonsyndromic deafness 70. Orthologous to human MCM2 (minichromosome maintenance complex component 2).