Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable SH3 domain binding activity and metalloendopeptidase activity. Predicted to be involved in positive regulation of angiogenesis and proteolysis. Predicted to act upstream of or within cell adhesion. Predicted to be located in nucleoplasm and plasma membrane. Is expressed in several structures, including bone; embryo mesenchyme; genitourinary system; gut; and meninges. Human ortholog(s) of this gene implicated in osteoarthritis. Orthologous to human ADAM12 (ADAM metallopeptidase domain 12).