Automated description from the Alliance of Genome Resources
Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in in utero embryonic development; nervous system development; and regulation of transcription by RNA polymerase II. Predicted to localize to the nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human HES3 (hes family bHLH transcription factor 3).