Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables coproporphyrinogen oxidase activity. A structural constituent of eye lens. Involved in heme A biosynthetic process; heme B biosynthetic process; and heme O biosynthetic process. Acts upstream of or within heme biosynthetic process. Located in membrane and mitochondrion. Is active in mitochondrial intermembrane space. Is expressed in embryo; liver; and yolk sac. Used to study hereditary coproporphyria. Human ortholog(s) of this gene implicated in hereditary coproporphyria and liver disease. Orthologous to human CPOX (coproporphyrinogen oxidase).