Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables axon guidance receptor activity. Involved in several processes, including corpus callosum development; neuron projection development; and tube morphogenesis. Acts upstream of or within central nervous system projection neuron axonogenesis and retinal ganglion cell axon guidance. Predicted to be located in plasma membrane. Predicted to be active in dendrite. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; heart; and sensory organ. Orthologous to human EPHB3 (EPH receptor B3).