Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including animal organ development; artery morphogenesis; and inorganic ion homeostasis. Predicted to localize to nucleus. Is expressed in several structures, including genital tubercle; limb; metanephros; nervous system; and sensory organ. Used to study Char syndrome; angle-closure glaucoma; and patent ductus arteriosus. Human ortholog(s) of this gene implicated in Char syndrome and patent ductus arteriosus. Orthologous to human TFAP2B (transcription factor AP-2 beta).