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Gene Ontology Classifications
Symbol
Name
ID
Cntn2
contactin 2
MGI:104518

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Automated description from the Alliance of Genome Resources (Release 5.3.0)

Enables carbohydrate binding activity and protein self-association. Involved in several processes, including clustering of voltage-gated potassium channels; establishment of protein localization to juxtaparanode region of axon; and reduction of food intake in response to dietary excess. Acts upstream of or within several processes, including adult walking behavior; neurogenesis; and positive regulation of adenosine receptor signaling pathway. Located in several cellular components, including main axon; myelin sheath; and neuronal cell body. Is active in axon initial segment. Is expressed in eye; nervous system; olfactory epithelium; and yolk sac. Used to study T-cell adult acute lymphocytic leukemia. Human ortholog(s) of this gene implicated in familial adult myoclonic epilepsy 5. Orthologous to human CNTN2 (contactin 2).



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Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement

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Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/26/2022
MGI 6.22
The Jackson Laboratory