Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables DNA-binding transcription factor activity and promoter-specific chromatin binding activity. Acts upstream of or within positive regulation of gene expression; positive regulation of transcription by RNA polymerase II; and retinal rod cell development. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Is expressed in eye. Used to study Leber congenital amaurosis 10 and enhanced S-cone syndrome. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 27. Orthologous to human NRL (neural retina leucine zipper).